OPTIMIZATION OF A DISTRIBUTED GENETIC ALGORITHM ON A CLUSTER OF WORKSTATIONS FOR THE DETECTION OF MICROCALCIFICATIONS

We have developed a method for the detection of clusters of microcalcifications in digital mammograms. Here, we present a genetic algorithm used to optimize the choice of the parameters in the detection scheme. The optimization has allowed the improvement of the performance, the detailed study of the influence of the various parameters on the performance and an accurate investigation of the behavior of the detection method on unknown cases. We reach a sensitivity of 96.2% with 0.7 false positive clusters per image on the Nijmegen database; we are also able to identify the most significant parameters. In addition, we have examined the feasibility of a distributed genetic algorithm implemented on a non-dedicated Cluster Of Workstations. We get very good results both in terms of quality and efficiency

A New Approach to Image Reconstruction in Positron Emission Tomography Using Artificial Neural Networks

This study investigates the possibility of using an Artificial Neural Network (ANN) for reconstructing Positron Emission Tomography (PET) images. The network is trained with simulated data which include physical effects such as attenuation and scattering. Once the training ends, the weights of the network are held constant. The network is able to reconstruct every type of source distribution contained inside the area mapped during the learning. The reconstruction of a simulated brain phantom in a noiseless case shows an improvement if compared with Filtered Back-Projection reconstruction (FBP). In noisy cases there is still an improvement, even if we do not compensate for noise fluctuations. These results show that it is possible to reconstruct PET images using ANNs. Initially we used a Dec Alpha; then, due to the high data parallelism of this reconstruction problem, we ported the learning on a Quadrics (SIMD) machine, suited for the realization of a small medical dedicated system. These results encourage us to continue in further studies that will make possible reconstruction of images of bigger dimension than those used in the present work (32 × 32 pixels)